B4GALT1 and pancreatic neoplasm: Experimental studies further confirm that silencing or knocking down B4GALT1 in PDAC cell lines leads to marked reductions in cell proliferation, migration, and invasive capacity, thus establishing its crucial role in pancreatic tumor progression (Chen et al., 2023; Cui et al., 2018; Tang et al., 2020; Wang et al., 2020).