Genetic risk factors such as mutations in Adenosine Triphosphate-BindingCassette, Subfamily A, Member 7 (ABCA7), APOE, Bridging Integrator 1 (BIN1), Triggeringreceptor expressed on myeloid cells 2 (TREM2), WWdomain-containing oxidoreductase (WWOX), CD2 associatedprotein (CD2AP), and FERM Domain Containing Kindlin-2(FERMT2), have been implicated in African Americanadults with AD. This evidence concerns the gene FERMT2 and Alzheimer disease.