In addition to this, quinone oxidoreductase 2 negatively regulates astrocyte autophagy and neuroprotection, thus playing a toxic role in dopaminergic degeneration; depletion of a single RNA‐binding protein, PTBP1, converts astrocytes into neurons thus reversing PD, and ursodeoxyn powder exerts a role in attenuating PD through inhibition of astrocyte‐mediated inflammation by the TGR5 [65, 66, 67, 69]. The gene discussed is GPBAR1; the disease is Parkinson disease.