GPT and metabolic dysfunction-associated steatotic liver disease: ALT is a crucial biomarker for liver function, with elevated serum ALT levels indicative of hepatic impairment.[33] It is worth noting that research conducted in the past 10 years has shown that the skeletal joint system is not just a simple load-bearing structure, but also an important endocrine organ that secretes cytokines that govern many organs throughout the body, including the liver.[34] A prospective cohort study involving 2055 community participants revealed that women with lower serum osteocalcin levels are at an increased risk of developing nonalcoholic fatty liver disease.