Next, we performed pseudotime analysis of the B1R‐expressing fibroblast subgroup, and the Pi16+ fibroblast subset served as the initiation end of differentiation, while the Adamdec1+ fibroblast subset differentiated as an intermediate transition state to the Cxcl14+ inflammatory cancer‐associated fibroblasts (iCAFs), indicating that the Bdkrb1+Adamdec1+ fibroblast subset underwent an inflammatory‐carcinoma phenotypic transition (Figure 7F). The gene discussed is ADAMDEC1; the disease is carcinoma.