For example, β‐catenin can promote the degradation of the ECM by activating MMPs (matrix metalloproteinases) or collagenases, providing conditions for the migration and invasion of tumor cells.[19, 20] Decorin, Fap, and β‐catenin were significantly upregulated in the inflammation‐cancer transformation model group, while KLK1 treatment significantly reduced their expression, and this improvement was inhibited in the SSR240612 group (Figure 7K,L). Here, FAP is linked to neoplasm.