In the previous results, we demonstrated a decrease in the expression of KLK1, which is considered one of the key enzymes involved in local inflammation, and Lys‐des‐Arg9‐BK, formed by proteolytic cleavage of bradykinin, which acts through the B1R, in acute and chronic colitis,[31] the effects of bradykinin are short‐lived in the body as it is rapidly hydrolyzed and degraded by enzymes such as bradykininase. This evidence concerns the gene KNG1 and Chronic colitis.