At initial presentation, all patients showed leukocytosis (WBC: 13.41–28.2 × 10^9/L), thrombocytosis (PLT: 359–594 × 10^9/L), anemia (HGB: 62–110 g/L), and elevated inflammatory markers (CRP: 100–166.68 mg/L; ESR: 19–112 mm/h; IL-6: 32.51–58.4 pg/mL). The gene discussed is CRP; the disease is thrombocytosis disease.