SIC, sepsis-induced coagulopathy; RR, respiratory rate; DM, diabetes mellitus; AF, atrial fibrillation; SAPS, Simplified Acute Physiology Score; IMV, invasive mechanical ventilation; PLT, platelet count; PT, prothrombin time; APTT, activated partial thromboplastin time; AG, anion gap; Lac, lactate. The gene discussed is F2; the disease is blood coagulation disease.