Changes in hippocampal neuroinflammatory markers were correlated with cognitive impairments (CA1: TNF-α, NF-κB1, IL-1β; DG: TNF-α, NF-κB1) and social deficits (CA1: TNF-α,IL-1β; DG: TNF-α, NF-κB1). The gene discussed is TNF; the disease is Cognitive impairment.