In addition, the proportion of Tregs (CD4+CD25+CD127- T cells) and their effector subsets (CD4+CD25+CD127-CD45RA-Foxp3high T cells29,30) within the CD4+ T cell population was higher in LS AML samples than in LC AML samples (Fig. 3d, e). This evidence concerns the gene IL7R and acute myeloid leukemia.