Moreover, affinity chromatography using succinylated wheat germ agglutinin (sWGA) beads, which selectively bind to O-GlcNAc, revealed a pronounced increase in O-GlcNAcylation levels of VEZF1 in human HCC tissue samples with relatively high GFAT1 expression (Fig. S4B). The gene discussed is VEZF1; the disease is hepatocellular carcinoma.