SQSTM1 and head and neck squamous cell carcinoma: Similarly, after overexpression of TFEB, the expression of LC3II in shACSS2 HNSCC, while the expression of SQSTM1 did not show a significant increase (Fig. 7A–D), and the fluorescence intensities of DQ-BSA and LysoSensor Green were significantly enhanced, indicating that the lysosomal function and autophagic flux of head and neck squamous cell carcinoma cells were partially improved (Fig. 7E–H).