For AFG3L2, these include autosomal dominant hereditary spinocerebellar ataxia type 28 (SCA28, MIM #610246) [9], autosomal recessive spastic ataxia 5 (SPAX5, MIM #614487) [10] and optic atrophy 12 (OPA12, MIM #618977) [11]. Here, AFG3L2 is linked to Ataxia.