LONP1 and CODAS syndrome: Intriguingly, pathogenic mutations within the N-terminal domain of HSPA9 have been linked to EVEN-PLUS syndrome (epiphyseal, vertebral, ear, nose, plus associated findings, EVPLS, MIM #616854), resulting in similar skeletal defects to LONP1-linked CODAS syndrome with additional craniofacial and developmental abnormalities [29].