In addition, CD4+ T cell subset analysis in tumor-infiltrating cells showed Th1 cells increased significantly more in the mice that received the hgp10025–33-pulsed bm12 mBMDCs than mice that received either the hgp10025–33-pulsed WT or bm1 mBMDC vaccines (Figure 1H), but levels of Th2 and Tfh cells and Tregs were unchanged (Supplemental Figure 3C). This evidence concerns the gene CD4 and neoplasm.