Neutrophils expressed high levels of Cd44, Il1b, Cxcl2, Cxcr2, Mmp9, and Ptgs2 mRNA, suggesting that they contribute to nonresolving renal inflammation during AKI-to-CKD transition (Figure 6B, Supplemental Figure 11, and Supplemental Data File 2). Here, CXCL2 is linked to chronic kidney disease.