Besides the scavenger receptor Cd36 (42), these AKI macrophages also expressed genes related to positive and negative immune modulation, and apoptotic cell clearance, including Cxcl16, Creb5 (43), Stab1 (44), Dab2 (45), Axl (46), Lilrb4 (47), and C1qa (48, 49) (Supplemental Figure 11B and Supplemental Data File 3). This evidence concerns the gene CREB5 and acute kidney injury.