Given the low concentrations of bile acids in lung tissue, such analyses will likely require highly sensitive techniques, such as liquid chromatography-mass spectrometry (LC-MS).In conclusion, although the upregulation of BAAT in the lungs of IPF patients has been documented, there is currently no direct evidence confirming its catalytic activity in this organ. The gene discussed is BAAT; the disease is idiopathic pulmonary fibrosis.