IL4R and eosinophilic esophagitis: Dupilumab is a human monoclonal antibody against the interleukin-4 receptor ɑ subunit effective in eosinophilic esophagitis (EoE) and other non-EoE eosinophilic gastrointestinal disorders.<h4>Methods</h4>We conducted a retrospective chart review to assess the histoclinical response of patients with EoC treated with dupilumab.<h4>Results</h4>Of 4 included patients, all 4 improved histologically, with 3 patients attaining histologic remission.