GSDMD and Sepsis: In LPS‐ and CLP‐induced sepsis models, we found that hepatic GSDMD did not exacerbate liver injury in septic mice, as well as the dysfunction of the liver (Figure S4, Supporting Information), so we speculated that in addition to playing a pyroptotic role, hepatic GSDMD played other roles in sepsis, such as pore‐forming activity.