IL1B and Sepsis: In addition, qPCR results showed that the mRNA levels of GSDMD, IL‐1β, caspase‐1, and caspase‐11 in liver tissues were significantly increased in LPS‐ and CLP‐induced sepsis models, and the serum concentration of IL‐1β in the sepsis model was also significantly increased (Figure 1B,C).