A large body of literature supports the positive effects of extracorporeal shock wave (ESWT) on functional and pain‐related outcomes in tendinopathy.[169] ESWT has been shown to enhance tendon angiogenesis by inducing VEGF expression through HIF1α stabilization and mobilizing endothelial progenitor cells from the bloodstream. The gene discussed is VEGFA; the disease is disease of the tendon.