A large body of literature supports the positive effects of extracorporeal shock wave (ESWT) on functional and pain‐related outcomes in tendinopathy.[169] ESWT has been shown to enhance tendon angiogenesis by inducing VEGF expression through HIF1α stabilization and mobilizing endothelial progenitor cells from the bloodstream. This evidence concerns the gene HIF1A and disease of the tendon.