In addition to the above‐mentioned enzymes, MMP‐3 and MMP‐13 are involved in the pathogenesis of tendinopathy being associated with excessive ECM turnover, which leads to structural and functional alterations.[57, 58] The upregulation of MMP‐13 contributes to the transition from acute tendon injury to chronic tendinopathy by perpetuating collagen degradation and interfering with tissue repair processes. The gene discussed is MMP3; the disease is disease of the tendon.