IL17A and alkaline phosphatase measurement: The results of the transcriptomic analysis showed that in the AP model group, 942 differentially expressed genes (431 upregulated and 511 downregulated) were significantly enriched in infection and inflammation-related pathways, such as the IL-17 and NOD-like receptor signaling pathways (Fig. 4), indicating that inflammatory response and immune activation are core pathological features of AP.