IL1B and type 1 diabetes mellitus: Analyses of publicly available T1D-related datasets34,35 showed that MOTS-c (mtRNR1) expression levels significantly decrease following treatment with SASP-related cytokines (FDR of 0.032, IFN-γ, IL1β, TNF14; FDR of 0.001, IFN-α15) (Fig. 2a and Supplementary Table 4).