MYC and cancer: The complexity of cancer progression involves numerous alterations in critical biological processes [2], including the dysregulation of key regulatory enzymes such as p53 and PTEN [3, 4], changes in transcriptional activities involving oncogenes like MYC [5], modifications in the protein levels of factors such as VEGF [6], and alterations in post-translational modifications like phosphorylation, acetylation and ubiquitination [7].