EPO and anemia: In this study we firstly investigated BM features in a large cohort of patients with AIHA, and showed a high prevalence of hypercellularity, dyserythropoiesis, and reticulin fibrosis (65%, 29% and 76% of patients, respectively) as well as of T-cell infiltrate (69% of subjects), being associated with inadequate bone marrow compensation (i.e., inappropriate reticulocyte response and endogenous erythropoietin levels), more severe anemia at onset, and higher number of therapy lines.