Examples of approved drugs include AGER, targeted by Oxytocin (used for preeclampsia) and Vitamin B12 (used for anemia caused by B12 deficiency); BRD2, targeted by Triazolam (a sedative for insomnia) and Alprazolam (for anxiety disorders and epilepsy); CEP43 targeted by Brivanib, investigated for breast cancer and liver cancer; S100A4 targeted by Sp-Met-1, explored for melanoma, colorectal cancer, and breast cancer; RPL14 targeted by Artenimol, used for treating uncomplicated plasmodium falciparum infections. This evidence concerns the gene S100A4 and insomnia measurement.