Analysis of the HIF‐2α expression levels per cell as well as the automated determination of zonal HIF‐2α–PDGFR‐β coexpression revealed no significant differences either between the renal zones – cortex, outer medulla and inner medulla – or between the conditions analysed for this study – normoxia, anaemia, PHDi administration and Vhl deletion in PDGFR‐β+ cells. The gene discussed is EPAS1; the disease is anemia (phenotype).