This observation is supported by another medical records-based study of patients with NSCLC, which showed that increasing weight loss during the 5 months after baseline and lower body mass index at baseline were associated with substantially worse outcomes, independent of other variables.17 In contrast, female sex and high PD-L1 status were associated with longer rwOS and rwTTNTD. The gene discussed is CD274; the disease is non-small cell lung carcinoma.