Numerous studies revealed that chemokines such as CXCL1, CXCL2, IL-8 (CXCL8), CXCL5, CXCL12, CCL2, and MIP-1α (CCL3) promote the infiltration of neutrophil to the tumoural microenvironment (61). This evidence concerns the gene CXCL2 and neoplasm.