The forest plots indicated that ALDOB level exhibited marked links to OS (HR = 2.065, 95% CI [1.330–3.205], P = 0.001) (Fig. 5A), DSS (HR = 2.352, 95% CI [1.340–4.129], P = 0.003) (Fig. 5B), and PFS (HR =2.003, 95% CI [1.268–3.163], P = 0.003) (Fig. 5C) in ccRCC. This evidence concerns the gene ALDOB and nonpapillary renal cell carcinoma.