Myosin VIIA plays an important role in retinal photoreceptor cells, the pigment epithelium and inner ear; therefore, mutations in MYO7A result in a spectrum of phenotypes ranging from Usher syndrome type 1B (8) to recessive non-syndromic hearing loss (DFNB2) and autosomal dominant hearing loss (DFNA11) (9). Here, MYO7A is linked to Usher syndrome.