Compared to AL amyloidosis (n = 4788), patients with ATTR amyloidosis (n = 8241) were older (median age, 77.4 vs. 62.5 years), more commonly male (median male proportion 87.5% vs. 61.0%), more frequently demonstrated cardiovascular comorbidities (Table 1), and displayed lower glomerular filtration rates (median eGFR, 59.9 vs. 65.4 mL/min), ejection fractions (median LVEF, 48.3% vs. 58.0%) and NT-proBNP levels (median, 3432 vs. 5664 pg/mL or ng/L). This evidence concerns the gene NPPB and AL amyloidosis.