PLK1 and colorectal carcinoma: In some of the PLK1 inhibitors, preclinical experiments were not conducted in CRC cell lines or xenografts, for example, TKM-080301, Scytonemin, SBE-13, LFM-A13, Purpurogallin, GW843682X, ZK-thiazolidinone, NMS-1, CYC-800, DAP-81, and LC-445.