According to in vitro tests, Codiaeum variegatum mediated nanoparticles showed the strongest multifunctional bioactivity, including increased scavenging of free radicals, targeted cytotoxicity against A549 lung cancer cells, and substantial inhibition of cyclooxygenase-1 and important enzymes that hydrolyze carbohydrates. The gene discussed is PTGS1; the disease is lung carcinoma.