EGFR and ependymoma: Moreover, besides unique mutational profiles of H3F3B p.K27I-mutant DMGs, DNA methylation analysis showed H3F3B p.K27I-mutant DMGs formed a cluster separate from all other entities with H3K27me3 loss including H3K27M mutant DMGs, EGFR-altered DMGs and posterior fossa group A (PFA) ependymoma.