Similar increases of Phf2 and its inflammation-related target genes were also observed in the cortex of 5xFAD (4 months old) mice from an RNAseq dataset (GSE168137) [46] (Fig. 4B) and in AD human postmortem tissues from a microarray study (GSE44770) [40] (Fig. 4B). This evidence concerns the gene PHF2 and Alzheimer disease.