To explore the impact of FAO activity in peroxisomes on pancreatic cancer, we compared the expression of ACAA1 and peroxisomal acyl-coenzyme A oxidase (ACOX1), the key proteins involved in FAO within peroxisomes, using commercially available pancreatic cancer tissue microarrays (Supplementary Fig. 1A–C). This evidence concerns the gene ACOX1 and familial pancreatic carcinoma.