We used a cross-sectional design involving 76 pediatric patients with PNS and a control group, and measured renal stiffness through SWE The clinical characteristics of the nephrotic group were collected, including age, sex, disease duration, clinical type, 24-h urine protein, plasma albumin, and the relationship with 2D-SWE value was analyzed. This evidence concerns the gene ALB and paraneoplastic neurologic syndrome.