DGE analysis revealed that liver Tregs, compared to tumor and PBMC Tregs, had higher expression of key genes linked to Treg recruitment and immune suppression (e.g., CXCR3, CCL3, CCL4, and CCL5) [38–41] (Supplementary Fig. S3C, Supplementary Table S5). This evidence concerns the gene CXCR3 and neoplasm.