Mollaoglu's study supports this notion, proposing that in the transformation from adenocarcinoma to squamous carcinoma, the deletion of NKX2‐1 or overexpression of SOX2 recruits tumour‐associated neutrophils, with the CXCL5 chemokine further promoting SOX2‐driven squamous cell transformation.58 Here, SOX2 is linked to squamous cell carcinoma.