Immunofluorescence (IF) analysis of tumor tissues from two mice per group on Day 1 revealed elevated c‐Cas1 levels and increased N‐GSDMD expression in G4 tumors, validating pyroptosis activation through the canonical c‐Cas1/GSDMD axis (Figure 5d; Figure S11, Supporting Information). The gene discussed is GSDMD; the disease is neoplasm.