SDC1 and Miyoshi myopathy: Treatment with BT-GSI (Fig. S3A; Data file S1) or the combo (Fig. S3B; Data file S2) led to the upregulation of apoptosis pathways and downregulation of cell cycle, DNA repair, and cell division biological processes, and downregulated the expression of Notch pathway targets and genes associated with cell proliferation in CD138+ MM cells compared to MM cells from the vehicle group (Figs. S3C-D).