WT1-specific CD8 + T-cells were present in all, but two patients (CML-PB-SC-1 and CML-PB-SC-5) showed higher frequencies, 3.8% total CD8 + T-cells, than the rest (Fig. 6C, D, Supplemental Table 13). This evidence concerns the gene WT1 and chronic myelogenous leukemia, BCR-ABL1 positive.