To detail the phenotypic features of epitope-specific CD8 + T-cells within CML patients in remission under TKI treatment, we analyzed patient scRNA+TCRαβ-seq data, resolving the cell clusters: NK-like TEMRA (FCGR3A, KIR2DL1/2, among cytolytic molecules GZMA, GZMH, PRF1) and effector/resident memory (CD69, CXCR6) T-cells as the most frequent phenotypes (Fig. 6A, B). Here, PRF1 is linked to chronic myelogenous leukemia, BCR-ABL1 positive.