The diagnosis of AIH is characterized by elevated levels of serum immunoglobulins, aspartate aminotransferase (AST), alanine aminotransferase (ALT), and one or more characteristic circulating autoantibodies, the histological presence of portal or lobular hepatitis with absence of viral hepatitis markers, and the responsiveness to immunosuppressive therapy [4–6, 9, 10]. This evidence concerns the gene GPT and autoimmune hepatitis.