Using FlyPhoneDB, a web-based tool for predicting cell-cell communications in Drosophila (Liu et al, 2022d), we analyzed ligand-receptor expression and identified three pathways with significant interaction scores (P < 0.05) between GFP-positive tumor cells and hemocytes: the epidermal growth factor receptor (EGFR), fibroblast growth factor receptor (FGFR), and platelet-derived growth factor receptor (PVR) pathways. This evidence concerns the gene EGFR and neoplasm.