MMP1 and neoplasm: Conversely, ectopic expression of an activated form of spz (spzACT) under the control of Cg-Gal4 (which labels both hemocytes and fat bodies) remotely accelerated QRasV12 tumor overgrowth (Fig. EV6A–C), increased the attachment of Spz-expressing hemocytes (Fig. EV6D), and upregulated the expression of dl, yki targets Diap1 and CycE (Fig. EV6E), as well as JNK target genes Mmp1 and P-JNK (Fig. EV6F).