Furthermore, H-151 not only inhibited the p-STING/p-IRF3 axis but also significantly reduced the expression of T cell infiltration and activation markers (CD3D and CD69) as well as anti-tumor factors (GZMB, IFNγ, and TNFα) (Fig. 3G–I, Fig. S4D). The gene discussed is CD3D; the disease is neoplasm.