Intracellular localization analysis revealed that STING localization in T cells was highly sensitive to NAD+ level fluctuations when mediated by Olaparib-treated OC cells, emphasizing the importance of Golgi-localized STING for downstream p-STING/p-IRF3 axis activation and enhanced anti-tumor function following exogenous stimulation (Fig. S6E). The gene discussed is IRF3; the disease is neoplasm.