In general, our results indicate that the m6A methylation level of FOXM1 mRNA increases following CDDP-induced DNA damage in HCC cells due to the high expression of WTAP, thereby increasing FOXM1 mRNA stability and leading to the subsequent elevation of FOXM1 protein expression, and eventually promoting HR efficiency (Fig. 7). The gene discussed is FOXM1; the disease is hepatocellular carcinoma.