In the bivariate analysis, several variables, such as mechanical ventilation, respiratory comorbidities, malaria comorbidities, metabolic disease, positive blood culture, increased AST, increased ALT, and increased disease severity scores, such as the modified early score (MEWS), national early warning score (NEWS) and SIRS score, and laboratory parameters, such as thrombocytopenia, prolonged PT and prolonged APTT, were found to be significantly associated with DIC development. The gene discussed is GPT; the disease is metabolic disease.