It has been observed that TDP‐43 can create fibrils of TDP‐43 and α‐synuclein together, by binding with several α‐synuclein species; furthermore, by coincubating cells of human neuroblastoma containing these fibrils, higher neurotoxicity was found compared with cells incubated with only TDP‐43 fibrils or α‐synuclein fibrils [39]. The gene discussed is TARDBP; the disease is neuroblastoma.