SHBG and metabolic dysfunction-associated steatotic liver disease: Currently, over 20 distinct hepatokines, including fetuin-A, angiopoietin-like 3 (ANGPTL3), fibroblast growth factor 21 (FGF21), sex hormone-binding globulin (SHBG), etc., have been described, and accumulating evidence points to their dysregulation in liver pathologies such as non-alcoholic fatty liver disease (NAFLD) [9,10].