Many revolutionary discoveries in cancer molecular biology followed: restriction enzymes passage of national cancer act (1971); hybridomas and monoclonal antibodies 50% tracking of cancer statistics by seer program (1975); cellular origin of retroviral oncogenes (1979); epidermal growth factor and receptor 1981 suppression of tumor growth by p53 (1984); G proteins and cell (1984), etc. [68]. The gene discussed is TP53; the disease is neoplasm.