Androgenic alopecia is one of the most common types of hair loss, which is caused by high concentrations of dihydrotestosterone (DHT) in the scalp, leading to progressive loss of the hair follicles.90 Extracellular vesicles from AD-MSCs carry miR-122-5p, which was shown to promote hair follicle growth via downregulating DHT inhibition of hair follicles, upregulating the expression of β-catenin, and downregulating the expression of TGF-β1.90 In DPCs, DHT downregulated the antiapoptotic protein BCL2 expression, whereas it upregulated pro-apoptotic protein Bax. This evidence concerns the gene TGFB1 and androgenetic alopecia.