Biomarker-Specific:- Surface markers (EpCAM, EGFRvIII) enable tumor enrichment (Laulagnier et al., 2004, Tauro et al., 2013)- Crosses BBB (Matsumoto et al., 2017)- Multi-analyte detection (DNA/RNA/protein) (Yu et al., 2021). Here, EPCAM is linked to neoplasm.